Dichloromethane → (4-Tritylsulfanylpyrrolidin-2-yl)methanol

HRID 301267Notes

Reaction equation

HRID 301267 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:33][OH:34])[CH2:10][CH:11]([S:13][C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[NH:8]1[CH:9]([CH2:33][OH:34])[CH2:10][CH:11]([S:13][C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22403996Tert-butyl 2-(hydroxymethyl)-4-tritylsulfanylpyrrolidine-1-carboxylate

Product 1

HCID 21461282(4-Tritylsulfanylpyrrolidin-2-yl)methanol

Sources & evidence

ORD record
ord-4cc323ee615146da96b23a3471dd6690
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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