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HRID30127

反应详情

EQUATION

反应方程式

HRID 30127 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)Cl
HCID6367

Acetyl chloride

C2H3ClO

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N.O=C(O)C(F)(F)F
HCID21070627

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)cc1C(=O)c1ccc(NC2CCN(C(C)=O)CC2)nc1N
HCID11653917

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt (Example 22) and acetyl chloride (Aldrich 98.5%) using the procedure described in Example 24. HRMS, observed: 387.1833, Calcd for (M+H)+: 387.1827.