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HRID30129

反应详情

EQUATION

反应方程式

HRID 30129 的结构方程式

REACTANTS

反应物

2
结构：CN=C=O
HCID12228

Methyl isocyanate

C2H3NO

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N.O=C(O)C(F)(F)F
HCID21070627

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)N1CCC(Nc2ccc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1
HCID11545824

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt (Example 22) and methyl isocyanate (Aldrich, 98%) using the procedure described in Example 24. HRMS, observed: 402.1940, Calcd for (M+H)+: 402.1936.