HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4,5-difluoro-2-methoxybenzene → (2-Amino-6-chloro-pyridin-3-yl)-(2,3-difluoro-6-methoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4,5-difluoro-2-methoxybenzene | HCID 2736262 | — |
| Reactant | 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide | HCID 58590824 | — |
| Product | (2-Amino-6-chloro-pyridin-3-yl)-(2,3-difluoro-6-methoxy-phenyl)-methanone | HCID 58590826 | — |
Reaction Steps
The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 2-bromo-4,5-difluoroanisole (Apollo) using the procedure described in Example 7. HRMS, observed: 298.0318, Calcd for M+: 298.0321.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423051B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-9e1bdbd13d854f31bcd46bf3854489c4 |
| Source note | uspto-grants-2008_09 |