Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30148Generated: October 29, 2026

1-Bromo-2,6-difluorobenzene → (2-Amino-6-chloro-pyridin-3-yl)-(2,6-difluoro-phenyl)-methanone

https://huagongshe.com/reaction/30148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2,6-difluorobenzeneHCID 123557—
Reactant2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamideHCID 58590824—
Product(2-Amino-6-chloro-pyridin-3-yl)-(2,6-difluoro-phenyl)-methanoneHCID 58590833—

Reaction Steps

The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 2-bromo-1,3-difluorobenzene (Aldrich) using the procedure described in Example 7. HRMS, observed: 268.0217, Calcd for M+: 268.0215.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423051B2
Source datasetuspto-grants-2008_09
ORD IDord-01d5fbb683b94a4b84c9036e8c746f35
Source noteuspto-grants-2008_09