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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 301565Generated: October 29, 2026

1-(Bromomethyl)-2-(trifluoromethyl)benzene → 6-Fluoro-2'-oxo-1'-[2-(trifluoromethyl)benzyl]-1',2'-dihydrospiro[1-benzofuran-3,3-indole]-5-carbonitrile

https://huagongshe.com/reaction/301565

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-2-(trifluoromethyl)benzeneHCID 123057—
Reactant2-(Bromomethyl)-5-(trifluoromethyl)furanHCID 2794605—
Reactant6-Fluoro-2'-oxo-1,2'-dihydrospiro[1-benzofuran-3,3'-indole]-5-carbonitrileHCID 59352271—
Reactant3-methylspiro[furo[3,2-f][1,2]benzisoxazole-5,3'-indol]-2'(1H)-oneHCID 59352453—
Product6-Fluoro-2'-oxo-1'-[2-(trifluoromethyl)benzyl]-1',2'-dihydrospiro[1-benzofuran-3,3-indole]-5-carbonitrileHCID 59352672—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ecc23edec56542a18ce46a208758fb6b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)