Dichloromethane → 3-(4-Bromo-2-fluoro-phenylamino)-5-formylaminomethyl-pyrazine-2-carboxylic acid methyl ester

HRID 301636Notes

Reaction equation

HRID 301636 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([CH2:23][NH:24][CH:25]=[O:26])[n:9][c:10]1[NH:11][c:12]1[c:13]([F:22])[cH:14][c:15]([Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:16][cH:17]1.[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:35][CH2:36][Cl:37].[O:27]=[C:28]1[N:29]([Br:34])[C:30](=[O:31])[CH2:32][CH2:33]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([CH2:23][NH:24][CH:25]=[O:26])[n:9][c:10]1[NH:11][c:12]1[c:13]([F:22])[cH:14][c:15]([Br:34])[cH:16][cH:17]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 67184N-bromobutanimideHCID 59140179HCID 59140179, compound

Product 1

HCID 591401763-(4-Bromo-2-fluoro-phenylamino)-5-formylaminomethyl-pyrazine-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-b6570500ede242489e49808afce02bd0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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