1-Methylimidazole → tert-butyl 4-hydroxy-4-(1-methyl-1H-imidazol-2-yl)piperidine-1-carboxylate
Reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:1][n:2]1[cH:3][n:4][cH:5][cH:6]1.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[CH3:1][n:2]1[c:3]([C:22]2([OH:25])[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]2)[n:4][cH:5][cH:6]1Participants
5
Sources & evidence
- ORD record
- ord-22ab3db00f874b1d8becb863f2ecef27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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