Hydrochloric Acid → 6-(4-Hydroxy-3-methoxy-phenyl)-2-(4-methoxy-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one

HRID 301939Notes

Reaction equation

HRID 301939 reaction equation
[CH3:1][O:2][c:3]1[c:4]([O:27][S:28]([c:29]2[cH:30][cH:31][c:32]([CH3:33])[cH:34][cH:35]2)(=[O:36])=[O:37])[cH:5][cH:6][c:7]([N:9]2[C:10](=[O:26])[c:11]3[c:12]([cH:15][c:16](-[c:18]4[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]4)[s:17]3)[CH2:13][CH2:14]2)[cH:8]1.[CH3:40][CH2:41][OH:42].[ClH:43].[K+:39].[OH-:38].[OH2:44]>>[CH3:1][O:2][c:3]1[c:4]([OH:27])[cH:5][cH:6][c:7]([N:9]2[C:10](=[O:26])[c:11]3[c:12]([cH:15][c:16](-[c:18]4[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]4)[s:17]3)[CH2:13][CH2:14]2)[cH:8]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 702EthanolHCID 813Potassium CationHCID 961HydroxideHCID 962WaterHCID 57649518Toluene-4-sulfonic acid 2-methoxy-4-[2-(4-methoxy-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-phenyl ester

Product 1

HCID 689509596-(4-Hydroxy-3-methoxy-phenyl)-2-(4-methoxy-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one

Sources & evidence

ORD record
ord-8c506b6088554ee89e29f4b3341dc818
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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