Hydrochloric Acid → 7-(5-Phenoxy-3-pyridyl)-1,7-diazaspiro[4,4]nonane

HRID 302186Notes

Reaction equation

HRID 302186 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH2:11][C:12]12[CH2:13][N:14]([c:17]1[cH:18][n:19][cH:20][c:21]([O:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[cH:22]1)[CH2:15][CH2:16]2.[CH3:33][CH2:34][OH:35].[ClH:30].[H:31][H:32].[OH-:36].[OH-:37].[Pd+2:38]>>[NH:8]1[CH2:9][CH2:10][CH2:11][C:12]12[CH2:13][N:14]([c:17]1[cH:18][n:19][cH:20][c:21]([O:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[cH:22]1)[CH2:15][CH2:16]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 222912051-Benzyl-7-(5-phenoxypyridin-3-yl)-1,7-diazaspiro[4.4]nonaneHCID 178418361HCID 178418361, compound

Product 1

HCID 115438947-(5-Phenoxy-3-pyridyl)-1,7-diazaspiro[4,4]nonane

Sources & evidence

ORD record
ord-bdc636f75e744c549f753cc216c68dca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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