Trifluoroacetic acid → 4-amino-N-(1-(4-chlorophenyl)-2-hydroxyethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][OH:10])[NH:11][C:12](=[O:13])[C:14]2([NH:29][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:15][CH2:16][N:17]([c:20]3[c:21]4[c:22]([n:23][cH:24][n:25]3)[nH:26][cH:27][cH:28]4)[CH2:18][CH2:19]2)[cH:6][cH:7]1.[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][OH:10])[NH:11][C:12](=[O:13])[C:14]2([NH2:29])[CH2:15][CH2:16][N:17]([c:20]3[c:21]4[c:22]([n:23][cH:24][n:25]3)[nH:26][cH:27][cH:28]4)[CH2:18][CH2:19]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-5307b38ff1344b69aa7173167d807325
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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