Dimethylformamide → ethyl 3-(5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)propanoate

HRID 302329Notes

Reaction equation

HRID 302329 reaction equation
[CH2:21]([CH3:22])[O:23][C:24]([CH2:25][CH2:26][Br:27])=[O:28].[NH2:1][c:2]1[n:3](-[c:8]2[cH:9][cH:10][c:11]([CH:18]3[CH2:19][CH2:20]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[c:4]([SH:7])[n:5][n:6]1.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[NH2:1][c:2]1[n:3](-[c:8]2[cH:9][cH:10][c:11]([CH:18]3[CH2:19][CH2:20]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[c:4]([S:7][CH2:26][CH2:25][C:24]([O:23][CH2:21][CH3:22])=[O:28])[n:5][n:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 68320Ethyl 3-bromopropionateHCID 178509206HCID 178509206, compound

Product 1

HCID 57811365ethyl 3-(5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)propanoate

Sources & evidence

ORD record
ord-b597e18534c04ee6807850131326590a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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