Methane → Pioglitazone

HRID 302564Notes

Reaction equation

HRID 302564 reaction equation
[C:32].[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][c:15]([CH:16]=[C:17]3[C:18](=[O:23])[NH:19][C:20](=[O:22])[S:21]3)[cH:24][cH:25]2)[n:7][cH:8]1.[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1.[Pd:33]>>[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][c:15]([CH2:16][CH:17]3[C:18](=[O:23])[NH:19][C:20](=[O:22])[S:21]3)[cH:24][cH:25]2)[n:7][cH:8]1

Participants

5

Reactant 4

HCID 297MethaneHCID 23938PalladiumHCID 312751,4-DioxaneHCID 533948925-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione

Product 1

HCID 4829Pioglitazone

Sources & evidence

ORD record
ord-270b1c6290864c85a9c9c7bb0b85bd7f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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