Nitrogen → HCID 68108833, compound

HRID 302630Notes

Reaction equation

HRID 302630 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6](-[c:8]2[n:9][n:10]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[c:11]3[n:12][c:13]([NH:17][CH2:18][CH2:19][N:20]4[CH2:21][CH2:22][O:23][CH2:24][CH2:25]4)[n:14][cH:15][c:16]23)[n:7]1.[Cl:34][c:35]1[cH:36][c:37]([CH2:38][NH2:39])[cH:40][cH:41][cH:42]1.[N:43]#[N:44].[O:101]1[CH2:102][CH2:103][O:104][CH2:105][CH2:106]1.[O:47]=[C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1.[O:65]=[C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)[CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[O:83]=[C:84]([CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1)[CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1.[Pd:45].[Pd:46]>>[c:2]1([NH:39][CH2:38][c:37]2[cH:36][c:35]([Cl:34])[cH:42][cH:41][cH:40]2)[cH:3][cH:4][cH:5][c:6](-[c:8]2[n:9][n:10]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[c:11]3[n:12][c:13]([NH:17][CH2:18][CH2:19][N:20]4[CH2:21][CH2:22][O:23][CH2:24][CH2:25]4)[n:14][cH:15][c:16]23)[n:7]1

Participants

7

Reactant 6

HCID 947NitrogenHCID 23938Palladium2×HCID 312751,4-DioxaneHCID 77802Benzenemethanamine, 3-chloro-HCID 95417Dibenzylidene acetone3×HCID 86667960[3-(6-bromo-pyridin-2-yl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-(2-morpholin-4-yl-ethyl)-amine

Product 1

HCID 68108833HCID 68108833, compound

Sources & evidence

ORD record
ord-59abc334b026422483b7b974c305ec70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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