Citric Acid → 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-2-[1-(2,6-dichlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-N-pyridin-2-ylpropanamide
Reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[Si:16]([O:17][CH:18]1[CH2:19][N:20]([CH2:22][CH:23]([C:24](=[O:25])[O:26][CH3:27])[O:28][c:29]2[c:30]3[c:31]([n:32][cH:33][n:34]2)[n:35](-[c:38]2[c:39]([Cl:45])[cH:40][cH:41][cH:42][c:43]2[Cl:44])[n:36][cH:37]3)[CH2:21]1)([CH3:46])[CH3:47].[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1.[Cl:69][CH2:70][Cl:71].[OH2:68].[OH:48][C:49]([CH2:50][C:51]([C:52](=[O:53])[OH:54])([CH2:55][C:56](=[O:57])[OH:58])[OH:59])=[O:60].[n:5]1[c:6]([NH2:11])[cH:7][cH:8][cH:9][cH:10]1>>[n:5]1[c:6]([NH:11][C:24]([CH:23]([CH2:22][N:20]2[CH2:19][CH:18]([O:17][Si:16]([C:12]([CH3:13])([CH3:14])[CH3:15])([CH3:46])[CH3:47])[CH2:21]2)[O:28][c:29]2[c:30]3[c:31]([n:32][cH:33][n:34]2)[n:35](-[c:38]2[c:39]([Cl:45])[cH:40][cH:41][cH:42][c:43]2[Cl:44])[n:36][cH:37]3)=[O:25])[cH:7][cH:8][cH:9][cH:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d3f8c37de1a7483f80bf88dc9de3cec0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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