HCID 67206140, compound → HCID 67206083, compound

HRID 30274Notes

Reaction equation

HRID 30274 reaction equation
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:8][CH:7]1[C:19]1[S:20][CH:21]=[CH:22][CH:23]=1)=[O:5])C>Cl>[CH2:12]([N:9]1[CH2:10][CH2:11][CH:6]([C:4]([OH:5])=[O:3])[CH:7]([C:19]2[S:20][CH:21]=[CH:22][CH:23]=2)[CH2:8]1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 1

HCID 67206140HCID 67206140, compound

Product 1

HCID 67206083HCID 67206083, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

The product from step b) (2.9 g, 8.8 mmol) was treated with 4 M HCl (200 ml) at 100° C. for 16 hours. Next, the reaction was evaporated to dryness, azeotroped with toluene (2×50 ml) and placed on the high vacuum to give the subtitle compound (2.9 g, 98%). MS calculated for C17H19NO2S−H 300, observed 300.

Workup

  1. customNext, the reaction was evaporated to dryness
  2. customazeotroped with toluene (2×50 ml)

Sources & evidence

ORD record
ord-bbfb62f3083a45d2b831ac2e73855e87
Source dataset
uspto-grants-2008_09
Patent number
US07423056B2

Reaction notes

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