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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 302941Generated: October 27, 2026

Piperazine → N-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxy-7-[3-piperazin-1-ylpropoxy]-quinazolin-4-amine

https://huagongshe.com/reaction/302941

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
ReactantDichloromethaneHCID 6344—
Reactant2-MethoxyethanolHCID 8019—
ReactantN-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-7-(3-chloropropoxy)-6-methoxyquinazolin-4-amineHCID 68882624—
ProductN-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxy-7-[3-piperazin-1-ylpropoxy]-quinazolin-4-amineHCID 68884133—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-48f647963c174d3d92298341b8566ad3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)