Ethyl Acetate → tert-Butyl 4-((2,3-diamino-5-chlorobenzoyloxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate
Reaction equation
[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH2:7][C:8]2([c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:28][c:29]([Cl:35])[cH:30][c:31]1[N+:32]([O-:33])=[O:34].[Pd:42]>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH2:7][C:8]2([c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:28][c:29]([Cl:35])[cH:30][c:31]1[NH2:32]Participants
4
Sources & evidence
- ORD record
- ord-1ba30741837145808a4115393566da37
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…