Hydrochloric Acid → 5-{1-[(3-methylphenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-(4-piperidinyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

HRID 303128Notes

Reaction equation

HRID 303128 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][O:48][CH2:49]1.[ClH:43].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:30]1[CH2:31][CH2:32][N:33]([C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH2:34][CH2:35]1)[cH:9][c:10]2-[c:11]1[cH:12][c:13]2[c:17]([cH:18][cH:19]1)[N:16]([C:20]([CH2:21][c:22]1[cH:23][c:24]([CH3:28])[cH:25][cH:26][cH:27]1)=[O:29])[CH2:15][CH2:14]2>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:30]1[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]1)[cH:9][c:10]2-[c:11]1[cH:12][c:13]2[c:17]([cH:18][cH:19]1)[N:16]([C:20]([CH2:21][c:22]1[cH:23][c:24]([CH3:28])[cH:25][cH:26][cH:27]1)=[O:29])[CH2:15][CH2:14]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 668238551,1-dimethylethyl 4-(4-amino-5-{1-[(3-methylphenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1-piperidinecarboxylate

Product 1

HCID 668236435-{1-[(3-methylphenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-(4-piperidinyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-e80b1014d4254af08ad287b6feb1d9d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…