Chloride → Benzyl 4-[(4-fluorophenyl)methyl]-4-hydroxypiperidine-1-carboxylate

HRID 303425Notes

Reaction equation

HRID 303425 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][C:14](=[O:17])[CH2:15][CH2:16]1.[Cl-:18].[F:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][Mg+:25])[cH:26][cH:27]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][C:14]([OH:17])([CH2:24][c:23]2[cH:22][cH:21][c:20]([F:19])[cH:27][cH:26]2)[CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 312ChlorideHCID 643496Benzyl 4-oxopiperidine-1-carboxylateHCID 178505755HCID 178505755, compound

Product 1

HCID 68502893Benzyl 4-[(4-fluorophenyl)methyl]-4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-86b5e853b9b14db699b8157dc1c57230
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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