Dichloromethane → (4-Isopropyl-piperazin-1-yl)-(4-methyl-5-naphthalen-1-yl-thiazol-2-yl)-methanone
Reaction equation
[CH2:36]([Cl:37])[Cl:38].[CH3:1][c:2]1[n:3][c:4]([C:17](=[O:18])[OH:19])[s:5][c:6]1-[c:7]1[cH:8][cH:9][cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12.[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH:20]([CH3:21])([CH3:22])[N:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1>>[CH3:1][c:2]1[n:3][c:4]([C:17](=[O:19])[N:26]2[CH2:25][CH2:24][N:23]([CH:20]([CH3:21])[CH3:22])[CH2:28][CH2:27]2)[s:5][c:6]1-[c:7]1[cH:8][cH:9][cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12Participants
5
Sources & evidence
- ORD record
- ord-b0f3590ca0bf452f8e68828af5ffd371
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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