Tetrahydrofuran → N-(1H-Indol-4-yl)-2-methylamino-N-phenyl-acetamide

HRID 303532Notes

Reaction equation

HRID 303532 reaction equation
[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:1][NH:2][CH2:3][C:4](=[O:5])[N:6]([c:7]1[c:8]2[cH:9][cH:10][n:11]([Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[c:12]2[cH:13][cH:14][cH:15]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[CH3:33][CH2:34][CH2:35][CH2:36][N+:37]([CH2:38][CH2:39][CH2:40][CH3:41])([CH2:42][CH2:43][CH2:44][CH3:45])[CH2:46][CH2:47][CH2:48][CH3:49].[F-:32]>>[CH3:1][NH:2][CH2:3][C:4](=[O:5])[N:6]([c:7]1[c:8]2[cH:9][cH:10][nH:11][c:12]2[cH:13][cH:14][cH:15]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 598318392-Methylamino-N-phenyl-N-(1-triisopropylsilanyl-1H-indol-4-yl)-acetamide

Product 1

HCID 59831661N-(1H-Indol-4-yl)-2-methylamino-N-phenyl-acetamide

Sources & evidence

ORD record
ord-c57a8ab9174e433282e426c0b871a6b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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