Dichloromethane → 6-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]-N-[2-(2-thienyl)ethyl]nicotinamide
Reaction equation
[C:35]([Cl:36])(=[O:37])[C:38]([CH3:39])([CH3:40])[CH3:41].[CH2:50]([Cl:51])[Cl:52].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH:8]([CH3:9])([CH3:10])[NH:11][c:12]1[c:13]([N:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[c:26]3[n:27][cH:28][c:29]([C:30](=[O:31])[OH:32])[cH:33][cH:34]3)[CH2:22][CH2:23]2)[n:14][cH:15][cH:16][cH:17]1.[s:42]1[c:43]([CH2:47][CH2:48][NH2:49])[cH:44][cH:45][cH:46]1>>[CH:8]([CH3:9])([CH3:10])[NH:11][c:12]1[c:13]([N:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[c:26]3[n:27][cH:28][c:29]([C:30](=[O:32])[NH:49][CH2:48][CH2:47][c:43]4[s:42][cH:46][cH:45][cH:44]4)[cH:33][cH:34]3)[CH2:22][CH2:23]2)[n:14][cH:15][cH:16][cH:17]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a8bf960299414025aafeb38fdc5f8465
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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