Bromide ion → 2,2,2-trifluoro-N-(6-methoxy-3-methylidene-1,2-dihydroinden-1-yl)acetamide

HRID 303634Notes

Reaction equation

HRID 303634 reaction equation
[Br-:42].[CH2:63]1[O:64][CH2:65][CH2:66][CH2:67]1.[CH3:16][C:17]([CH3:18])([O-:19])[CH3:20].[CH3:43][P+:44]([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)([c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[F:22][C:23]([C:24](=[O:25])[NH:26][CH:27]1[CH2:28][C:29](=[O:38])[c:30]2[cH:31][cH:32][c:33]([O:36][CH3:37])[cH:34][c:35]21)([F:39])[F:40].[K+:21].[N:1]([CH:4]1[c:2]2[c:3]([cH:5][cH:6][c:7]([O:8][CH3:9])[cH:10]2)[CH2:11][CH:12]1[OH:13])=[N+:14]=[N-:15].[OH2:41]>>[CH2:4]=[C:29]1[CH2:28][CH:27]([NH:26][C:24]([C:23]([F:22])([F:39])[F:40])=[O:25])[c:35]2[c:30]1[cH:31][cH:32][c:33]([O:36][CH3:37])[cH:34]2

Participants

9

Reactant 8

HCID 259Bromide ionHCID 813Potassium CationHCID 962WaterHCID 8028TetrahydrofuranHCID 74506TriphenylmethylphosphoniumHCID 38382832,2,2-trifluoro-N-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetamideHCID 45749132-Methylpropan-2-olateHCID 86622330(1RS,2RS)-1-azido-6-methoxy-2,3-dihydro-1H-inden-2-ol

Product 1

HCID 874613032,2,2-trifluoro-N-(6-methoxy-3-methylidene-1,2-dihydroinden-1-yl)acetamide

Sources & evidence

ORD record
ord-63a5f5e02c60482fa472b919c6b60ef6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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