Acetate → 2,3-Dihydro-5-[4-(phenylmethoxy)phenyl]-1H-inden-1-one

HRID 303925Notes

Reaction equation

HRID 303925 reaction equation
[Br:18][c:19]1[cH:20][c:21]2[c:25]([cH:26][cH:27]1)[C:24](=[O:28])[CH2:23][CH2:22]2.[C:56]([O-:57])(=[O:58])[CH3:59].[C:61]([O-:62])(=[O:63])[CH3:64].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([B:15]([OH:16])[OH:17])[cH:13][cH:14]1.[CH:29]1([P:30]([CH:31]2[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]2)[CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]2)[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47]1.[F-:48].[K+:49].[O:50]1[CH2:51][CH2:52][O:53][CH2:54][CH2:55]1.[Pd+2:60]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12](-[c:19]2[cH:20][c:21]3[c:25]([cH:26][cH:27]2)[C:24](=[O:28])[CH2:23][CH2:22]3)[cH:13][cH:14]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 813Potassium CationHCID 28179Fluoride IonHCID 312751,4-DioxaneHCID 75806TricyclohexylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 5206955-Bromo-1-indanoneHCID 27343144-Benzyloxy-phenylboronic acid

Product 1

HCID 211000302,3-Dihydro-5-[4-(phenylmethoxy)phenyl]-1H-inden-1-one

Sources & evidence

ORD record
ord-5ecc819a25f24e32bcc93902b657650a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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