1,4-Dioxane → HCID 178498832, compound

HRID 304187Notes

Reaction equation

HRID 304187 reaction equation
[CH3:23][O:24][C:25](=[O:26])[c:27]1[n:28][cH:29][c:30]([Cl:33])[n:31][cH:32]1.[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][c:11]([N:16]3[CH2:17][CH:18]([CH3:22])[NH:19][CH2:20][CH2:21]3)[c:12]([CH3:15])[c:13]2[CH3:14])[cH:6][cH:7]1.[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10][c:11]([N:16]3[CH2:17][CH:18]([CH3:22])[N:19]([c:30]4[cH:29][n:28][c:27]([C:25]([O:24][CH3:23])=[O:26])[cH:32][n:31]4)[CH2:20][CH2:21]3)[c:12]([CH3:15])[c:13]2[CH3:14])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 406081Methyl 5-chloropyrazine-2-carboxylateHCID 671767473-(4-Fluorophenyl)-4,5-dimethyl-6-(3-methylpiperazin-1-yl)pyridazine

Product 1

HCID 178498832HCID 178498832, compound

Sources & evidence

ORD record
ord-c1f9b4008c954c1ab9c6f4e68c054ed6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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