Dichloromethane → 4-[5-Fluoro-1-(2-trimethylsilylethanesulfonyl)indol-3-yl]piperidine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][n:16]([S:24](=[O:25])(=[O:26])[CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[c:17]3[cH:18][cH:19][c:20]([F:23])[cH:21][c:22]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:40]([Cl:41])[Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][n:16]([S:24](=[O:25])(=[O:26])[CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[c:17]3[cH:18][cH:19][c:20]([F:23])[cH:21][c:22]23)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-3cd34232c7a6403fb66ae457013e7ce9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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