Acetic Acid → (4-Hydroxy-3-methoxyphenyl)(2-(trifluoromethyl)pyridin-3-yl)methanone

HRID 304369Notes

Reaction equation

HRID 304369 reaction equation
[BrH:29].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:27][CH3:28])[cH:11][c:12]([C:15](=[O:16])[c:17]2[c:18]([C:23]([F:24])([F:25])[F:26])[n:19][cH:20][cH:21][cH:22]2)[cH:13][cH:14]1.[CH3:30][C:31](=[O:32])[OH:33].[Cl:34][CH2:35][Cl:36]>>[OH:8][c:9]1[c:10]([O:27][CH3:28])[cH:11][c:12]([C:15](=[O:16])[c:17]2[c:18]([C:23]([F:24])([F:25])[F:26])[n:19][cH:20][cH:21][cH:22]2)[cH:13][cH:14]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6344DichloromethaneHCID 67037150(4-Benzyloxy-3-methoxy-phenyl)-(2-trifluoromethyl-pyridin-3-yl)-methanone

Product 1

HCID 68703345(4-Hydroxy-3-methoxyphenyl)(2-(trifluoromethyl)pyridin-3-yl)methanone

Sources & evidence

ORD record
ord-b723571eb7174711a07845253390e00b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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