Water → (3-Methylpyrrolidin-3-yl)(pyrrolidin-1-yl)methanone

HRID 304540Notes

Reaction equation

HRID 304540 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][CH2:18][CH2:19]2)([CH3:20])[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:28][CH2:29][Cl:30].[F:21][C:22]([F:23])([F:24])[C:25]([OH:26])=[O:27].[OH2:31]>>[NH:8]1[CH2:9][C:10]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][CH2:18][CH2:19]2)([CH3:20])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 596056303-Methyl-3-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 63140531(3-Methylpyrrolidin-3-yl)(pyrrolidin-1-yl)methanone

Sources & evidence

ORD record
ord-52c99f98c866424b979632cb4ce765e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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