N,N-Diethylacetamide → 7-(3-Chloropyridin-2-yl)-N-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-2-(methoxymethyl)pyrido[3,4-d]pyrimidin-4-amine
Reaction equation
[CH2:48]([N:49]([CH2:50][CH3:51])[C:52](=[O:53])[CH3:54])[CH3:55].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[Cl:34][c:35]1[n:36][cH:37][cH:38][cH:39][c:40]1[Cl:41].[F:10][C:11]([c:12]1[cH:13][cH:14][c:15]([NH:18][c:19]2[c:20]3[c:21]([n:22][c:23]([CH2:25][O:26][CH3:27])[n:24]2)[CH2:28][NH:29][CH2:30][CH2:31]3)[cH:16][cH:17]1)([F:32])[F:33].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[F:10][C:11]([c:12]1[cH:13][cH:14][c:15]([NH:18][c:19]2[c:20]3[c:21]([n:22][c:23]([CH2:25][O:26][CH3:27])[n:24]2)[CH2:28][N:29]([c:35]2[n:36][cH:37][cH:38][cH:39][c:40]2[Cl:41])[CH2:30][CH2:31]3)[cH:16][cH:17]1)([F:32])[F:33]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0fe2dffde69645b5b29b22cf7e263f6f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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