Dichloromethane → 1-[4-(2-phenyl-9H-imidazo[1,2-d]pyrido[2,3-b][1,4]benzodiazepin-3-yl)phenyl]cyclopropanamine
Reaction equation
[Cl:49][CH2:50][Cl:51].[OH:42][C:43]([C:44]([F:45])([F:46])[F:47])=[O:48].[c:1]1(-[c:7]2[n:8][c:9]3[n:10]([c:24]2-[c:25]2[cH:26][cH:27][c:28]([C:31]4([NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:32][CH2:33]4)[cH:29][cH:30]2)-[c:11]2[c:12]([n:20][cH:21][cH:22][cH:23]2)[NH:13][c:14]2[c:15]-3[cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][c:9]3[n:10]([c:24]2-[c:25]2[cH:26][cH:27][c:28]([C:31]4([NH2:34])[CH2:32][CH2:33]4)[cH:29][cH:30]2)-[c:11]2[c:12]([n:20][cH:21][cH:22][cH:23]2)[NH:13][c:14]2[c:15]-3[cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
4
Sources & evidence
- ORD record
- ord-9c3d4fb76b80463a8652d555f25c628a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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