Hydrochloric Acid → 1-(3-Aminopropyl)-4-methylpiperazine

HRID 304691Notes

Reaction equation

HRID 304691 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:12](=[O:13])[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]3[C:20]2=[O:21])[CH2:6][CH2:7]1.[CH3:32][CH2:33][OH:34].[CH3:35][OH:36].[Cl:37][CH2:38][Cl:39].[ClH:25].[K+:26].[K+:27].[NH2:23][NH2:24].[O-:28][C:29]([O-:30])=[O:31].[OH2:22]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][CH2:10][NH2:11])[CH2:6][CH2:7]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 702EthanolHCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 6344DichloromethaneHCID 9321HydrazineHCID 19660Carbonate IonHCID 202494272-[3-(4-Methylpiperazin-1-yl)propyl]-1H-isoindole-1,3(2H)-dione

Product 1

HCID 783281-(3-Aminopropyl)-4-methylpiperazine

Sources & evidence

ORD record
ord-aa2a5fabd8b54773beb57577539c0600
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…