Methanesulfonic Acid → 7-(N-benzylmorpholin-2-ylmethoxy)-4-(2-bromo-4-fluorophenoxy)-6-methoxyquinazoline
Reaction equation
[Br:21][c:22]1[c:23]([O:24][c:25]2[n:26][cH:27][n:28][c:29]3[cH:30][c:31]([OH:37])[c:32]([O:35][CH3:36])[cH:33][c:34]23)[cH:38][cH:39][c:40]([F:42])[cH:41]1.[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][CH:15]([CH2:19][OH:20])[O:16][CH2:17][CH2:18]1.[CH3:1][S:2]([OH:3])(=[O:4])=[O:5]>>[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][CH:15]([CH2:19][O:20][c:31]2[cH:30][c:29]3[n:28][cH:27][n:26][c:25]([O:24][c:23]4[c:22]([Br:21])[cH:41][c:40]([F:42])[cH:39][cH:38]4)[c:34]3[cH:33][c:32]2[O:35][CH3:36])[O:16][CH2:17][CH2:18]1Participants
4
Sources & evidence
- ORD record
- ord-e8772442f5814523bf8d4d44146cd341
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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