2-Thiophenecarboxaldehyde → [4-Chloro-2-(2-chloro-phenoxy)-pyrimidin-5-yl]-thiophen-2-yl-methanol
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH:16]([NH:17][CH:18]([CH3:19])[CH3:20])([CH3:21])[CH3:22].[Cl:1][c:2]1[n:3][c:4]([O:8][c:9]2[c:10]([Cl:15])[cH:11][cH:12][cH:13][cH:14]2)[n:5][cH:6][cH:7]1.[Li:23].[s:24]1[c:25]([CH:29]=[O:30])[cH:26][cH:27][cH:28]1>>[Cl:1][c:2]1[n:3][c:4]([O:8][c:9]2[c:10]([Cl:15])[cH:11][cH:12][cH:13][cH:14]2)[n:5][cH:6][c:7]1[CH:29]([c:25]1[s:24][cH:28][cH:27][cH:26]1)[OH:30]Participants
6
Sources & evidence
- ORD record
- ord-9e8f6d31943d4ebc8caba59c4c2a175f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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