HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-((6-Bromopyridin-2-yl)methyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 6-Bromopyridine-2-carbaldehyde | HCID 2757009 | — |
| Product | 4-((6-Bromopyridin-2-yl)methyl)morpholine | HCID 23438147 | 61.4% |
Reaction Steps
The title compound was prepared in a manner similar to that described in Example 18, Step C, using 6-bromo-pyridine-2-carbaldehyde (0.415 g, 2.23 mmol) and morpholine (0.195 g, 2.23 mmol). The crude product was purified (SiO2: 0-3% 2 M NH3 in MeOH/DCM) to give the title compound (0.352 g, 61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423147B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-fa5bebcc2d7d478e86bde5e4dc353426 |
| Source note | uspto-grants-2008_09 |