Dichloromethane → 4-chloro-2-{[3-(diethylamino)propyl]amino}-8-(2,6-difluorophenyl)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[CH2:24]([CH3:25])[N:26]([CH2:27][CH2:28][CH2:29][NH2:30])[CH2:31][CH3:32].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([S:8]([CH3:9])=[O:10])[n:7]1)[n:11](-[c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[c:12](=[O:15])[cH:13][cH:14]2.[Cl:40][CH2:41][Cl:42]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH:30][CH2:29][CH2:28][CH2:27][N:26]([CH2:24][CH3:25])[CH2:31][CH3:32])[n:7]1)[n:11](-[c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[c:12](=[O:15])[cH:13][cH:14]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c91eb6c67f544a8a847cd27251b37ed6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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