Diethyl Ether → (4-Chloro-3-fluoro-2-methoxyphenyl)[2-(trifluoromethyl)oxiranyl]methanone
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[Cl:13][c:14]1[c:15]([F:28])[c:16]([O:26][CH3:27])[c:17]([C:18](=[O:19])[N:20]([O:21][CH3:22])[CH3:23])[cH:24][cH:25]1.[F:1][C:2]([CH:3]1[CH2:4][O:5]1)([F:6])[F:7]>>[F:1][C:2]([C:3]1([C:18]([c:17]2[c:16]([O:26][CH3:27])[c:15]([F:28])[c:14]([Cl:13])[cH:25][cH:24]2)=[O:19])[CH2:4][O:5]1)([F:6])[F:7]Participants
7
Sources & evidence
- ORD record
- ord-bf0df4a3fc1f4aeeb232e8547a1fe9f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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