Tetrahydrofuran → 5-(5-Bromo-2-fluorophenyl)-6,6-difluoro-5-methyl-1,4-oxazepane-3-thione
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:19])[c:6]([C:8]2([CH3:18])[NH:9][C:10](=[O:17])[CH2:11][O:12][CH2:13][C:14]2([F:15])[F:16])[cH:7]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([P:26]2(=[S:29])[S:27][P:28]([c:30]3[cH:31][cH:32][c:33]([O:34][CH3:35])[cH:36][cH:37]3)(=[S:38])[S:39]2)[cH:40][cH:41]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:19])[c:6]([C:8]2([CH3:18])[NH:9][C:10](=[S:29])[CH2:11][O:12][CH2:13][C:14]2([F:15])[F:16])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-8d472f0f366a465eae55002a9d948c05
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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