Borane → Methyl 13-cyclohexyl-6-(hydroxymethyl)-5-methyl-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepine-10-carboxylate

HRID 305327Notes

Reaction equation

HRID 305327 reaction equation
[BH3:34].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:30](=[O:31])[O:32][CH3:33])[cH:12][c:13]3[n:14]3[c:20]2-[c:19]2[c:18]([cH:24][cH:23][cH:22][cH:21]2)[N:17]([CH3:25])[CH:16]([C:26](=[O:27])[O:28][CH3:29])[CH2:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:30](=[O:31])[O:32][CH3:33])[cH:12][c:13]3[n:14]3[c:20]2-[c:19]2[c:18]([cH:24][cH:23][cH:22][cH:21]2)[N:17]([CH3:25])[CH:16]([CH2:26][OH:27])[CH2:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 66674609Dimethyl 13-cyclohexyl-5-methyl-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepine-6,10-dicarboxylate

Product 1

HCID 66674023Methyl 13-cyclohexyl-6-(hydroxymethyl)-5-methyl-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepine-10-carboxylate

Sources & evidence

ORD record
ord-2817159a41244f7d88bd9eb9c7ef00b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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