Methanol → 3,3-bis(hydroxymethyl)-1-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile
Reaction equation
[CH3:45][OH:46].[NH2:41][CH2:42][CH2:43][NH2:44].[OH:1][CH2:2][C:3]1([CH2:32][OH:33])[CH2:4][C:5]([n:7]2[n:8][cH:9][c:10](-[c:12]3[c:13]4[c:14]([n:15][cH:16][n:17]3)[n:18]([CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:19][cH:20]4)[cH:11]2)([CH2:29][C:30]#[N:31])[CH2:6]1.[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[OH:1][CH2:2][C:3]1([CH2:32][OH:33])[CH2:4][C:5]([n:7]2[n:8][cH:9][c:10](-[c:12]3[c:13]4[c:14]([n:15][cH:16][n:17]3)[nH:18][cH:19][cH:20]4)[cH:11]2)([CH2:29][C:30]#[N:31])[CH2:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6a61e51afd314393a6f5b5117946c9b2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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