Borane → 4-(2-Chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

HRID 305588Notes

Reaction equation

HRID 305588 reaction equation
[BH3:1].[Cl:2][c:3]1[c:4]([CH:9]2[C:10]([C:26](=[O:27])[O:28][CH2:29][CH3:30])=[C:11]([CH2:20][O:21][CH2:22][C:23](=[O:24])[OH:25])[NH:12][C:13]([CH3:19])=[C:14]2[C:15](=[O:16])[O:17][CH3:18])[cH:5][cH:6][cH:7][cH:8]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[Cl:2][c:3]1[c:4]([CH:9]2[C:10]([C:26](=[O:27])[O:28][CH2:29][CH3:30])=[C:11]([CH2:20][O:21][CH2:22][CH2:23][OH:24])[NH:12][C:13]([CH3:19])=[C:14]2[C:15](=[O:16])[O:17][CH3:18])[cH:5][cH:6][cH:7][cH:8]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028TetrahydrofuranHCID 13457220{[4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl]methoxy}acetic acid

Product 1

HCID 703535674-(2-Chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

Sources & evidence

ORD record
ord-fbdd428c50f24ef5b74195cd4cfeeabc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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