Sodium ion → tert-Butyl 4-cyano-4-(2,4-difluorophenyl)piperidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][CH2:9][Cl:13])[CH2:11][CH2:12][Cl:10])=[O:14].[F:15][c:16]1[c:17]([CH2:23][C:24]#[N:25])[cH:18][cH:19][c:20]([F:22])[cH:21]1.[H-:27].[Na+:26].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]1[CH2:8][CH2:9][C:23]([c:17]2[c:16]([F:15])[cH:21][c:20]([F:22])[cH:19][cH:18]2)([C:24]#[N:25])[CH2:12][CH2:11]1)=[O:14]Participants
6
Sources & evidence
- ORD record
- ord-6111e80d2e6a4f3fb864f37565184f7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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