Dichloromethane → 2-[1-(biphenyl-4-ylsulfonyl)piperidin-4-yl]-1H-benzimidazole

HRID 306137Notes

Reaction equation

HRID 306137 reaction equation
[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:41][CH2:42][Cl:43].[NH:17]1[CH2:18][CH2:19][CH:20]([c:23]2[n:24][c:25]3[c:26]([nH:27]2)[cH:28][cH:29][cH:30][cH:31]3)[CH2:21][CH2:22]1.[c:1]1(-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[Cl:10])[cH:5][cH:6]1>>[c:1]1(-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:17]2[CH2:18][CH2:19][CH:20]([c:23]3[nH:24][c:25]4[c:26]([n:27]3)[cH:28][cH:29][cH:30][cH:31]4)[CH2:21][CH2:22]2)[cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 74192(1,1'-Biphenyl)-4-sulphonyl chlorideHCID 81531DiisopropylethylamineHCID 7158102-(piperidin-4-yl)-1H-1,3-benzodiazole

Product 1

HCID 445656382-[1-(biphenyl-4-ylsulfonyl)piperidin-4-yl]-1H-benzimidazole

Sources & evidence

ORD record
ord-d3b7a8f63c6345f9a53e250dd18278b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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