Dichloromethane → 2-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)-8-((4-methoxyazepan-4-yl)methoxy)quinoline

HRID 306141Notes

Reaction equation

HRID 306141 reaction equation
[Cl:45][CH2:46][Cl:47].[OH:38][C:39]([C:40]([F:41])([F:42])[F:43])=[O:44].[n:1]1[n:2][c:3](-[c:10]2[n:11][c:12]3[c:13]([O:20][CH2:21][C:22]4([O:36][CH3:37])[CH2:23][CH2:24][N:25]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:26][CH2:27][CH2:28]4)[cH:14][cH:15][cH:16][c:17]3[cH:18][cH:19]2)[n:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[n:1]1[n:2][c:3](-[c:10]2[n:11][c:12]3[c:13]([O:20][CH2:21][C:22]4([O:36][CH3:37])[CH2:23][CH2:24][NH:25][CH2:26][CH2:27][CH2:28]4)[cH:14][cH:15][cH:16][c:17]3[cH:18][cH:19]2)[n:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86654367tert-Butyl 4-((2-([1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-yloxy)methyl)-4-methoxyazepane-1-carboxylate

Product 1

HCID 672305252-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)-8-((4-methoxyazepan-4-yl)methoxy)quinoline

Sources & evidence

ORD record
ord-7ac87969b9be446788aa16fde4742e7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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