Dichloromethane → 2,2-Dimethylpropionic acid piperidin-4-ylmethyl ester

HRID 306232Notes

Reaction equation

HRID 306232 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][C:16]([C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:29][CH2:30][Cl:31].[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28]>>[NH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][C:16]([C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 689141014-(2,2-Dimethylpropionyloxymethyl)piperidine-1-carboxylic acid t-butyl ester

Product 1

HCID 689120142,2-Dimethylpropionic acid piperidin-4-ylmethyl ester

Sources & evidence

ORD record
ord-c69b65eff39f4e7884dcec8505b1419f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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