Diethyl Ether → tert-Butyl 3-(4-bromophenyl)-1-hydroxypropan-2-ylcarbamate
Reaction equation
[Al+3:22].[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]([NH:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[C:16](=[O:17])[OH:18])[cH:19][cH:20]1.[CH3:27][CH2:28][O:29][CH2:30][CH3:31].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]([NH:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:16][OH:17])[cH:19][cH:20]1Participants
6
Sources & evidence
- ORD record
- ord-42882ee1ac474f258961f5565cce80a9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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