Dichloromethane → 2-(1-Amino-2-naphthalen-2-ylethyl)-5-phenyl-1,3-thiazole-4-carboxamide

HRID 306337Notes

Reaction equation

HRID 306337 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]([CH2:10][c:11]1[cH:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]2[cH:19][cH:20]1)[c:21]1[s:22][c:23](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:24]([C:26](=[O:27])[NH2:28])[n:25]1)([CH3:5])([CH3:6])[CH3:7].[CH2:42]([Cl:43])[Cl:44].[OH:35][C:36]([C:37]([F:38])([F:39])[F:40])=[O:41]>>[NH2:8][CH:9]([CH2:10][c:11]1[cH:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]2[cH:19][cH:20]1)[c:21]1[s:22][c:23](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:24]([C:26](=[O:27])[NH2:28])[n:25]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22949410tert-butyl N-[1-(4-carbamoyl-5-phenyl-1,3-thiazol-2-yl)-2-naphthalen-2-ylethyl]carbamate

Product 1

HCID 229493262-(1-Amino-2-naphthalen-2-ylethyl)-5-phenyl-1,3-thiazole-4-carboxamide

Sources & evidence

ORD record
ord-eb1cde0cd0d54946b79e72ef4223490a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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