Dichloromethane → 1-(2-Fluoroethyl)piperazine

HRID 306414Notes

Reaction equation

HRID 306414 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][N:18]([CH2:21][CH2:22][F:23])[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[CH2:24]([Cl:25])[Cl:26].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][N:18]([CH2:21][CH2:22][F:23])[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21082715tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate

Product 1

HCID 210826721-(2-Fluoroethyl)piperazine

Sources & evidence

ORD record
ord-b6f500bad343440095396be60181c905
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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