3-Amino-1-propanol → 2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-N-(3-hydroxypropyl)-4,4,6,6-tetramethyl-4,6-dihydrothieno[2,3-c]furan-3-carboxamide

HRID 306746Notes

Reaction equation

HRID 306746 reaction equation
[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([C:19](=[O:20])[OH:21])[c:9]3[c:10]([s:18]2)[C:11]([CH3:16])([CH3:17])[O:12][C:13]3([CH3:14])[CH3:15])[c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][cH:24][cH:25]1.[OH:30][CH2:31][CH2:32][CH2:33][NH2:34]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([C:19](=[O:20])[NH:34][CH2:33][CH2:32][CH2:31][OH:30])[c:9]3[c:10]([s:18]2)[C:11]([CH3:16])([CH3:17])[O:12][C:13]3([CH3:14])[CH3:15])[c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][cH:24][cH:25]1

Participants

3

Reactant 2

HCID 90863-Amino-1-propanolHCID 67300640HCID 67300640, compound

Product 1

HCID 247727452-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-N-(3-hydroxypropyl)-4,4,6,6-tetramethyl-4,6-dihydrothieno[2,3-c]furan-3-carboxamide

Sources & evidence

ORD record
ord-856136d4371e41fe8aeb2ed5cd9b07bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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