Acetic Acid → 1-(4-bromophenyl)-N,N-dimethylpiperidin-4-amine

HRID 306990Notes

Reaction equation

HRID 306990 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[C:22]([O:23][BH-:24]([O:25][C:26](=[O:27])[CH3:28])[O:29][C:30](=[O:31])[CH3:32])(=[O:33])[CH3:34].[CH3:15][NH:16][CH3:17].[CH3:18][C:19](=[O:20])[OH:21].[CH3:36][OH:37].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:38][CH2:39][Cl:40].[Na+:35]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][CH:11]([N:16]([CH3:15])[CH3:17])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 176Acetic AcidHCID 674DimethylamineHCID 887MethanolHCID 923Sodium ionHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 2724942TriacetoxyborohydrideHCID 246921481-(4-Bromophenyl)piperidin-4-one

Product 1

HCID 667303771-(4-bromophenyl)-N,N-dimethylpiperidin-4-amine

Sources & evidence

ORD record
ord-a1f27b1115e14056a481b45f14ba1c83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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